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It seems high intensity RE stimulates basophilic cells of the anterior pituitary to release luteinizing hormone (LH) from gonadotrophs in the anterior pituitary which then acts as the primary regulator of testosterone secretion from the Leydig cells of the testes (Fry and Kraemer, 1997). These pathways lead to increases in muscle protein synthesis (MPS) and net protein accretion which result in an increase in muscle mass. RE has been shown to increase the concentration of these hormones which activate several different signaling pathways in the muscle. Testosterone also effects the development of bone, connective and neural tissues (Hoffman et al., 2009), leading to increased muscle strength, power, endurance, and hypertrophy in a dose-dependent manner (Sinha-Hikim et al., 2006; Kraemer et al., 2017). Though Sensoril is the least costly of the three branded extracts, it’s not very common in ashwagandha supplements. 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