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Further studies incorporating measurements of caffeine blood level and investigation of a subjective expectation of coffee drinking as a cognitive enhancer may clarify the dose–response relationship and main contributor of the FC changes. Here, we compared the properties of FC before and after coffee consumption to analyze the acute effects of caffeine on the brain network and its impact on neurocognitive function using graph-theoretic analysis of EEG data. It infuses the brain and body with an alerting energy signal. Starting on the far left of the figure, the circadian rhythm begins to increase its activity a few hours before you wake up. To impress upon you the effects of caffeine, I footnote esoteric research conducted in the 1980s by NASA. When this happens, you are assaulted with a most forceful adenosine-trigger urge to sleep—the aforementioned caffeine crash. 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