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Efficacy of participant treatment blinding was examined by askingparticipants to predict group allocation (placebo, ashwagandha, or uncertain) atthe completion of each phase of the study (Weeks 8 and 16). Additionally, current intake of anyherbal preparations or a known hypersensitivity to ashwagandha, herbalsupplements, or other herbs and spices also resulted in ineligibility forstudy participation. The mental and physical effects of ashwagandha have beeninvestigated in several research studies, with identified positive effects in reducingstress and anxiety (Pratte,Nanavati, Young, & Morley, 2014) and increasing memory and cognition(Choudhary, Bhattacharyya, &Bose, 2017). Given the influence of steroid hormones such as testosteroneand DHEA on mental and physical well-being, health-related quality of life, and diseasemorbidity and mortality, treatments options to slow their progressive decline as men agemay be prudent. 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