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A separate study of men ages examined the effect of taking both L-arginine and pycnogenol (chemicals taken from French pine trees) together for ED treatment.20 Participants were given L-arginine for one month; nothing happened. In one study, a third of men reported that they experienced significant improvement in sexual function while using L-arginine.19 L-Arginine is an amino acid we naturally have within our bodies. This is why we like to see supplement companies perform heavy metal testing, which is rare among volume pills but more common with fertility supplements. Due to a risk of over-supplementation and toxicity for certain ingredients (often vitamin D or zinc), we do not recommend combining a multivitamin with any volume pills. Ingredients like shilajit, L-arginine, maca, and ginseng aren’t in the average multivitamin, and there is some clinical evidence that they can help with sexual function. 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