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PFAS are synthetic compounds that are suspected endocrine-disrupting chemicals having the ability to cause dysfunction to hormonally regulated body systems . However, the role of phthalate metabolites as potential risk factors of ED remains to be elucidated clearly. A summary of the research studies conducted on honey and its reported effects on serum and urinary levels of testosterone. For example, it was shown that male albino Wistar rats orally supplemented with caffeic acid at 50 mg kg−1 had higher serum levels of testosterone and luteinizing hormone compared with the control . Similarly, patients taking centrally acting medications such as antidepressants or antipsychotics should avoid using such products which may cause unwanted herb-drug interactions and hence side effects, one of which may be sexual dysfunction. 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