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Although vitamin B12 showed a significant positive linear relationship with TT concentrations, there was no evidence of a similar association with the other reproductive hormones (FSH, LH, prolactin, and estradiol). Our findings show a positive linear association between vitamin B12 and serum TT concentrations. Results from the logistic regression analyses assessing the association between tertiles of vitamin B12 concentrations (with the lowest tertile as the reference group) and the clinical status of reproductive hormones (with normal hormone concentrations as the reference group) are presented in Table 4 and Supplemental Figure 2. The relationship depicted is the association between serum ascorbic acid concentration and square root of reproductive hormones (FSH, LH, TT, and prolactin). Studies show that most people regain weight after two years. A systematic review article examines the outcomes of reframing the reasons for weight loss. 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