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"I wouldn’t recommend people take them because we don’t know what the side effects are. We don’t know what the downsides are. We don’t know how long you need to take them," he said. Schmidt echoed that sentiment, noting it's crucial to prioritize your health and safety. Raj said there are too many unknowns about the alternative products. The supplement is tested by NSF, an independent testing organization, for safety and dosage claims; and is "thoroughly vetted by third party scientific and medical experts for claims and safety," the company added. “If you can just go buy a supplement and lose 20 or 30, 40 pounds, you couldn’t hear the end of it. “They contain extracts, maybe from fruits or vegetables, that purport to boost your body’s natural GLP-1. They do not contain an agonist or a mimicking hormone,” Raj said in a TODAY segment that aired on Thursday, Sept. 19. 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